Publications

Autophagy maintains high endothelial venule identity and function during inflammation - Jacobs KA, Hua Y, Nikolakopoulos AP, Gupta S, Vella G, Domingues Laranjeiro AF, Bonnereau J, Guyot M, Sassano ML, Mourao L, Cansiz F, Allies G, Van Baren N, Lucas S, Kawashima H, Sondermann W, Rambow F, Tasdogan A, Scheele CLGJ, Agostinis P, Bergers G.  - 2026 - Immunity - PubMed

Stepwise Differentiation of Mouse Embryonic Stem Cells Into Murine Blood Vessel Organoids With Endothelial Lineage Tracing for Quality Control - Guelfi S, Bopp S, Bergers G - 2026 - Bio Protocol Journal  - PubMed

Distinct tumor immune microenvironmental (TIME) landscapes drive divergent immunotherapy responses in glioblastoma - Weng L, Gopalan KS, Guyot M, Vanmechelen M, Nazari P, Duhamel M, Donisi C, Pallarés Moratalla C, Garg AD, White K, Byrne AT, Lambrechts D, De Smet F, Bergers G - 2026 - Neuro Oncol - PubMed

Murine vascular organoids are responsive and adaptable 3D systems with cellular heterogeneity and dynamic plasticity - Guelfi S, Gopalan KS, Maene P, John Robbert D, Pallarés Moratalla C, Vella G, Nobis M, Mourao L, Bourdely P, van der Veer BK, Koh KP, Mazzone M, Scheele CLGJ, Bergers G -  2025 - Science Advances - PubMed

Guidelines for the assessment of high endothelial venule functionality and health - Jacobs KA, Bergers G - 2025 - Methods Cell Biol - PubMed

The Pan-tumor vasculature under the transcriptomic magnifying glass - Skandha Gopalan K, Bergers G - 2024 - Cancer Research - PubMed

Targeting the tumour vasculature: from vessel destruction to promotion - Guelfi S, Hodivala-Dilek K, Bergers G - 2024 - Nature Reviews Cancer - PubMed

The ins and outs of microglial cells in brain health and disease - Pallarés Moratalla, C., Bergers, G. - 2024 - Frontiers in Immunology - PubMed

High endothelial venules in cancer: regulation, function and therapeutic implication - Vella G, Hua Y and Bergers G - 2023 - Cancer Cell - PubMed

Anticancer immunotherapies transition postcapillary venules into high-endothelial venules that generate TCF1+ T lymphocyte niches through a feed-forward loop in cancer - Hua, Y.*, Vella, G.*, Rambow, F., Allen, E., Antoranz Martinez, A., Duhamel, M., Takeda, A., Jalkanen, S., Junius, S., Smeets, A., Nittner, D., Laoui, D., Dimmeler, S., Hehlgans, T., Liston, A., Bosisio, F.M., Floris, G., Laoui, D., Hollmén, M., Lambrechts, D., Merchiers, P., Bosisio, F.M., Marine, J-C, Schlenner, S., Bergers, G.# - 2022 - Cancer Cell - PubMed

R-2-HG assists IDH1-mutant solid tumors by promoting angiogenesis - Bögürcü-Seidel N and Bergers G - 2022 - Cell Res - PubMed

Anticancer immunotherapies transition postcapillary venules into high-endothelial venules that generate TCF1+ T lymphocyte niches through a feed-forward loop in cancer - Hua, Y.*, Vella, G.*, Rambow, F., Allen, E., Antoranz Martinez, A., Duhamel, M., Junius, S., Smeets, A., Nittner, D., Laoui, D., Dimmeler, S.? Hehlgans, T., Liston, A., Floris, G., Lambrechts, D., Merchiers, P., Bosisio, F.M., Marine, J-C, Schlenner, S., Bergers, G.# - 2021 - Cancer Cell - submitted // BioRXiv

High endothelial venules: a vascular perspective on tertiary lymphoid structures in cancer - Vella G, Guelfi S and Bergers G - 2021 - Frontiers in immunology - PubMed

The metabolism of cancer cells during metastasis - Bergers, G and Fendt, S-M - 2021 - Nature Reviews Cancer - PubMed

Tumors versus chronic wounds: an immune cell's perspective. - Hua, Y and Bergers, G - 2019 - Frontiers in Immunology - Pubmed

Peptide-guided nanoparticles for glioblastoma targeting - Säälik P, Lingasamy P, Toome K, Mastandrea I, Rousso-Noori L, Tobi A, Simon-Gracia L, Hunt H, Paiste P, Kotamraju VR, Bergers G, Asser T, Rätsep T, Ruoslahti E, Bjerkvig R, Friedmann-Morvinski D, Teesalu T - 2019 - Journal of Controlled Release - Pubmed

Regulation of Blood and Lymphatic Vessels by Immune Cells in Tumors and Metastasis. - Mazzone, M, and Bergers G - 2019 - Annu Rev Physio - Pubmed

Where have all the T-cells gone? - Vella, G. and Bergers, G. - 2018 - Immunity - Pubmed

A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma - Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, Obernier K, Alvarez-Buylla A, Bergers G, Phillips JJ, Nam DH, Bertozzi CR, Weaver VM - 2018 - Nature Cell Biology - Pubmed

The reciprocal function and regulation of tumor vessels and immune cells offers new therapeutic opportunities in cancer - Missiaen R, Mazzone M, and Bergers G - 2018 - Seminars in Cancer Biology - Pubmed

Vascular targeting of LIGHT normalizes blood vessels in primary brain cancer and induces intratumoural high endothelial venules - He, B., Jabouille, A., Steri, V., Johansson-Percival, A., Michael, I.P., Kotamraju, V.R., Junckerstorff, R., Nowak, A.K., Hamzah, J., Lee, G., Bergers, G., and Ganss, R. - 2018 - Journal of Pathology - Pubmed

Cross-activating c-Met/beta 1 integrin complex drives metastasis and invasive resistance in cancer - Jahangiri, A., Nguyen, A., Chandra, A., Sidorov, M.K., Yagnik, G., Rick, J., Han, S.W., Chen, W., Flanigan, P.M., Schneidman-Duhovny, D., Mascharak, S., De Lay, M., Imber, B., Park, C.C., Matsumoto, K., Lu, K., Bergers, G., Sali, A., Weiss, W.A., and Aghi, M.K. - 2017 - Proc Natl Acad Sci U S A - Pubmed

Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation - Allen E, Jabouille A, Rivera LB, Lodewijckx I, Missiaen R, Steri V, Feyen K, Tawney J, Hanahan D, Michael IP & Bergers G - 2017 - Science Translational Medicine - Pubmed

Intratumoral myeloid cells regulate responsiveness and resistance to antiangiogenic therapy - Rivera LB, Meyronet D, Hervieu V, Frederick MJ, Bergsland E and Bergers G - 2015 - Cell Reports - Pubmed